The Van Lehn group develops and applies molecular simulation techniques to characterize, predict, and engineer the properties of synthetic and biological soft materials. We employ a combination of simulation techniques across multiple time and length scales to uncover relationships between nanoscale properties and macroscopic behavior. We particularly focus on multicomponent systems with spatially varying interfacial properties, studying the behavior of both synthetic (e.g., nanoparticles, surfactants, and peptides) and biological (e.g., proteins, lipid bilayers, and biopolymers) systems. The insight acquired from our simulations can be used to inform the design new soft materials for a range of applications, including drug delivery, environmental sensing, plastic recycling, catalysis, and self-assembly.