David J. Beebe

Associate Chair of Research & Faculty Development and Professor

Room: 6009
Wisconsin Institute for Medical Research
1111 Highland Drive
Madison, WI 53705

Ph: (608) 262-2260
Fax: (608) 265-6905
djbeebe@wisc.edu

Primary Affiliation:
Biomedical Engineering

Additional Affiliations:
Mechanical Engineering, Materials Science Program, Biomedical Engineering Center for Translational Research, Biotechnology Training Program, Chemistry-Biology Interface Training Program, Chemistry-Biology Interface Training Program, Genome Sciences Training Program, University of Wisconsin Comprehensive Cancer Center, Wisconsin Institutes for Medical Research


Profile Summary

Our goal is a holistic approach to understanding cell behavior that integrates in vitro cellular scale engineering to recapitulate important in vivo microenvironmental characteristics in ways that provide biological insights, aid in diagnosis/treatment and enhance discovery. While our particular interests center around cancer biology, our work has broad potential application across cell biology.

Education

  • Ph.D. 1994, University of Wisconsin - Madison

Research Interests

  • Microfluidics
  • Cell & Cancer biology

Awards, Honors and Societies

  • IEEE EMBS Early Career Achievement Award, 2001
  • Romnes Award, UW-Madison, 2003
  • Fellow, Royal Society of Chemistry, 2005
  • Lab on a Chip, Royal Society of Chemistry and Corning, Pioneers of Miniaturization Prize, 2006
  • Fellow, American Institute for Medical and Biological Engineering (AIMBE), 2007
  • Founding Scientific Editor, Integrative Biology, Royal Society of Chemistry, 2009

Publications

  • Beebe, D. J., J. S. Moore, J. M. Bauer, Q. Yu, R. H. Liu, C. Devadoss, B-H. Jo, \"Functional structures for autonomous flow control inside micro fluidic channels,\" Nature, vol. 404, pp. 588-590, 2000.
  • Beebe, D. J., J. Moore, Q. Liu, R. H. Liu, M. L. Kraft, B-H. Jo and C. Devadoss, \"Microfluidic Tectonics: A comprehensive construction platform for microfluidic systems,\" Proceedings of the National Academy of Science, vol. 97, No. 25, pp. 13488-13493, 2000.
  • Liu, R. H., K. V. Sharp, M. G. Olsen, M. Stremler, J. G. Santiago, R. J. Adrian, H. Aref, D. J. Beebe, \"A Passive three-dimensional \'C-shape\' helical micromixer,\" Journal of Microelectromechanical Systems, vol. 9, No. 2, pp. 190-198, 2000.
  • Zhao, B., J. S. Moore and D. J. Beebe, \"Surface-directed liquid flow inside microchannels,\" Science, vol. 291, pp. 1023-1026, 2001.
  • Walker, G. M. and D. J. Beebe, \"A passive pumping method for microfluidic devices,\" Lab on a Chip, vol. 2, pp. 131-134, 2002.
  • Walker, G. M., H. Zeringue and D. J. Beebe, \"Microenvironment design considerations for cellular scale studies,\" Lab. Chip., vol. 4, pp. 91-97, 2004.
  • Atencia, J. and D. J. Beebe, \"Controlled microfluidic interfaces,\" Nature, vol. 437, pp. 648-655, 2005.
  • Dong, L., A. K. Agarwal, D. J. Beebe and H. Jiang,\"Smart liquid microlenses,\" Vol. 442, pp. 551-554, Nature, 2006.
  • Yu, H., C. M. Alexander and D. J. Beebe, \"Understanding microchannel culture: parameters involved in soluble factor signaling,\"Lab on a Chip, Vol. 7, pp. 726-730, 2007.
  • Paguirigan A, and D. J. Beebe, \"Microfluidics, meet cell biology:bridging the gap by validation and application of microscale techniques for cell biological assays,\" Bioessays, Vol. 30, pp. 811-821, 2008.
  • Domenech. M., H. Yu, J. Warrick, N. M. Badders, I. Meyvantsson, C. M. Alexander, and D. J. Beebe, \"Cellular observations enabled by microculture: paracrine signaling and population demographics,\" Integrative Biology, Vol. 1, pp. 267 - 274, 2009.
  • Young, E. W. K and D. J. Beebe, \"Fundamentals of microfluidic cell culture in controlled microenvironments,\" Chemical Society Reviews, Vol. 39, pp. 136-148, 2010.

Courses

Summer 2014

  • ME 890 - PhD Research and Thesis

  • BME 389 - Honors in Research
  • BME 990 - Research and Thesis
  • BME 890 - Pre-dissertation Research
  • BME 790 - Master\'s Research and Thesis
  • BME 699 - Advanced Independent Study
  • BME 399 - Independent Study
  • BME 389 - Honors in Research
  • BME 990 - Research and Thesis
  • BME 890 - Pre-dissertation Research
  • BME 790 - Master\'s Research and Thesis
  • BME 699 - Advanced Independent Study
  • BME 399 - Independent Study
  • ME 990 - Dissertator Research and Thesis
  • ME 890 - PhD Research and Thesis
  • ME 990 - Dissertator Research and Thesis
  • ME 890 - PhD Research and Thesis
  • BME 990 - Research and Thesis
  • BME 890 - Pre-dissertation Research
  • BME 790 - Master\'s Research and Thesis
  • BME 399 - Independent Study
  • Profile Summary

    Our goal is a holistic approach to understanding cell behavior that integrates in vitro cellular scale engineering to recapitulate important in vivo microenvironmental characteristics in ways that provide biological insights, aid in diagnosis/treatment and enhance discovery. While our particular interests center around cancer biology, our work has broad potential application across cell biology.


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