Pamela Kreeger

Assistant Professor

Room: 4553
Wi Institute Medical Research
1111 Highland Ave
Madison, WI 53705

Ph: (608) 890-2915
Fax: (608) 265-9239

Primary Affiliation:
Biomedical Engineering

Additional Affiliations:
Molecular and Environmental Toxicology Center

Research Interests

  • Systems Biology
  • Ovarian Cancer
  • Cellular Engineering
  • Tissue Engineering
  • Women's Health


  • Postdoctoral Fellowship, Biological Engineering, MIT, 2005-2008
  • Ph.D. Chemical Engineering, Northwestern University, 2005
  • B.S. Chemistry, Valparaiso University, 2000

Research Interests

  • Systems Biology
  • Ovarian Cancer
  • Cellular Engineering
  • Tissue Engineering
  • Women\'s Health

Awards, Honors and Societies

  • 2014 NIH New Innovator
  • 2014 Cellular and Molecular Bioengineering Young Innovator
  • 2014 Chemical Communications Emerging Investigator
  • 2013 James G. Woodburne Award for Excellence in Teaching
  • 2013 American Cancer Society Research Scholar
  • 2010 NSF CAREER Award
  • 2008 American Cancer Society Postdoctoral Fellowship
  • 2006 Anna Fuller Fund Fellowship in Molecular Oncology
  • 2005 Northwestern University Fellow
  • 2002 National Defense Science and Engineering Graduate Fellowship
  • 2001 Cabell Fellow


  • D. Tian, P.K. Kreeger. Analysis of the quantitative balance between insulin-like growth factor (IGF)-1 ligand, receptor, and binding protein levels to predict cell sensitivity and therapeutic efficacy. BMC Systems Biology. 8: 98, 2014.
  • K. Pollock, T.J. Jaraczewski, M.J. Carroll, D.I. Lebovic, P.K. Kreeger. Endometriotic epithelial cell response to macrophage-secreted factors is dependent on extracellular matrix context. Cellular and Molecular Bioengineering. 7, p. 409-420, 2014. 
  • M.J. Carroll, L.E. Stopfer, P.K. Kreeger. A simplified culture system to examine soluble factor interactions between mammalian cells. Chemical Communications. 50, p. 5279-5281, 2014.
  • P.K. Kreeger. Using Partial Least Squares Regression to Analyze Cellular Response Data. Science Signaling. 6, tr7, 2013.
  • R. Liu, K.Z. Vang, P.K. Kreeger, S.H. Gellman, K.S. Masters. Experimental and Computational Analysis of Cellular Interactions with Nylon-3-bearing Substrates. J Biomed Mater Res A. 100, p 2750-9, 2012.
  • R.D. Prasasya, K. Vang, P.K. Kreeger. A Multivariate Model of ErbB Network Composition Predicts Ovarian Cancer Cell Response to Canertinib. Biotechnology and Bioengineering. 109, p 213-224, 2012.
  • R.D. Prasasya, D. Tian, P.K. Kreeger. Analysis of Cancer Signaling Networks by Systems Biology to Develop Therapies. Seminars in Cancer Biology. 21, p 200-206, 2011.
  • P.K. Kreeger, Y. Wang, K.M. Haigis, D.A. Lauffenburger. Integration of Multiple Signaling Pathway Activities Resolves K-RAS / N-RAS Mutation Paradox in Colon Epithelial Cell Response to Inflammatory Cytokine Stimulation. Integrative Biology. 2, p 202-208, 2010.
  • P.K. Kreeger, D.A. Lauffenburger. Cancer Systems Biology: A Network Modeling Perspective. Carcinogenesis. 31, p 2-8, 2010.
  • P.K. Kreeger, R. Mandhana, S.K. Alford, K.M. Haigis, D.A. Lauffenburger. RAS Mutations Affect Tumor Necrosis Factor-Induced Apoptosis in Colon Carcinoma Cells via ERK-Modulatory Negative and Positive Feedback Circuits Along with Non-ERK Pathway Effects. Cancer Research. 69, p 8191-8199, 2009.
  • M. Xu, P.K. Kreeger, L.D. Shea, and T.K. Woodruff. Tissue Engineered Follicles Produce Live, Fertile Offspring. Tissue Engineering. 12, p 2739-2746, 2006.
  • S.K. Bristol-Gould, P.K. Kreeger, C.G. Selkirk, S.M. Kilen, K.E. Mayo, L.D. Shea, and T.K. Woodruff. Fate of the Initial Follicle Pool: Empirical and Mathematical Evidence Supporting its Sufficiency for Adult Fertility. Developmental Biology. 298, p 149-154, 2006.
  • S.K. Bristol-Gould, P.K. Kreeger, C.G. Selkirk, S.M. Kilen, R.W. Cook, J.L. Kipp, L.D. Shea, K.E. Mayo, and T.K. Woodruff. Postnatal Regulation of Germ Cells by Activin: the Establishment of the Initial Follicle Pool. Developmental Biology. 298, p 132-148, 2006.
  • P.K. Kreeger, J.W. Deck, T.K. Woodruff, and L.D. Shea. The In Vitro Regulation of Ovarian Follicle Development Using Alginate-Extracellular Matrix Gels. Biomaterials. 27, p 714-723, 2006.
  • P.K. Kreeger, N.N. Fernandes, T.K. Woodruff, and L.D. Shea. Regulation of Mouse Follicle Development by Follicle Stimulating Hormone in a Three-Dimensional In Vitro Culture System is Dependent on Follicle Stage and Dose. Biology of Reproduction. 73, p 942-950, 2005.
  • P.K. Kreeger, T.K. Woodruff, and L.D. Shea. Murine Granulosa Cell Morphology and Function are Regulated by a Synthetic Arg-Gly-Asp Matrix. Molecular and Cellular Endocrinology. 205, p 1-10, 2003.


Fall 2015-2016

  • BME 890 - Pre-dissertation Research
  • BME 790 - Master\'s Research and Thesis
  • BME 699 - Advanced Independent Study
  • BME 399 - Independent Study

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